Toxicological Profile for Synthetic Vitreous Fibers
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2. Relevance to Public Health 2.1 Background and Environmental Exposures to Synthetic Vitreous Fibers in the United States
Synthetic vitreous fibers are inorganic fibrous materials, manufactured principally from glass, rock, minerals, slag, and processed inorganic oxides. Synthetic vitreous fibers are manufactured by several processes, all of which involve cooling of a stream of high-temperature, molten inorganic oxides. Commercially important synthetic vitreous fibers are primarily silica-based, but contain variou...
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Interspecies differences in pulmonary and pleural responses to the inhalation of natural mineral and synthetic vitreous fibers have been observed in chronic and subchronic studies. However, the reasons for these differences are not clearly understood. There are also fiber-specific differences in the outcome of chronic inhalation exposure to natural mineral and synthetic vitreous fibers. Whether...
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